Platelia™ Dengue NS1 Ag

The Platelia Dengue NS1 Ag assay, developed by Bio-Rad in partnership with the Pasteur Institute in France, is an ELISA test and enables the detection of NS1 dengue virus antigen as soon as the first clinical signs appear. The ability to detect the presence of the NS1 antigen offers earlier detection of the infection compared to the conventional serological methods that are currently used. The time saved is at least 6 days after a primary infection.

Test performance of the Platelia Dengue NS1 Ag assay has been confirmed through evaluations led by Bio-Rad teams as well as by reference laboratories of countries directly concerned by the disease, including Vietnam, Thailand, Singapore, India, Brazil and Guyana.

The sensitivity of the Platelia Dengue NS1 Ag assay has been shown to be 91% effective based on 177 retrospective sera from patients with current dengue infection confirmed by RT-PCR. Specificity was evaluated on 618 specimens including samples from 563 blood donors, 55 hospitalised patients and 200 potentially interfering sera. No positive results were observed in the test sample, providing 100% specificity.

In addition, Platelia Dengue NS1 Ag assay detects, with the same efficiency, all strains of the dengue virus. Early diagnosis, thanks to the detection of dengue virus NS1 antigen, will allow for considerable improvements in patient care. It will enable earlier suitable treatment to avoid serious complications and will help limit the spread of the disease.

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